21 August 2026

Sacubitril valsartan sodium hemipentahydrate

•    Drug Class: antihypertensive
•    Chemical Formula: C48H58N6O8.5/2H2O.3Na
•    CAS Number: 936623-90-4
•    Indications: Sacubitril is a neprilisin inhibitor, and valsartan is an angiotensin II receptor blocker, 
indicated:
-    to reduce the risk of cardiovascular death and hospitalization for heart failure in adult patients with chronic heart failure. Benefits are most clearly evident in patients with left ventricular ejection fraction (LVEF) below normal. 
-    for the treatment of symptomatic heart failure with systemic left ventricular systolic dysfunction in pediatric patients aged one year and older.

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